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Chronic pain is a prevalent condition that causes functional impairment and emotional suffering. To allay pain-induced suffering, opioids are often prescribed for chronic pain management.

A subset of chronic pain patients misuse prescription opioids as a means of regulating negative emotions. However, opioid misuse may result in deficits in emotion regulation strategies like reappraisal by virtue of the deleterious effects of chronic opioid exposure.

In the last 20 years, the immigrant population has increased by “70 percent to about 43 million,” making up about “13 percent of the population” with “one in every four Americans” being “either an immigrant or the child of one” with estimates that “one million immigrants have come legally to the United States each year” since 2000 (Preston, 2016, p. 1). The Pew Research Center (2008) illustrated that by 2050 one in five Americans (19%) will be foreign born; non-Hispanic Whites who comprised 67% of the population in 2005 will now be 47%; Hispanics will rise from 14% of the population in 2005 to 29%; Blacks will represent around 13%; and Asians, who were 5% of the population in 2005, will be at 9%. By 2050, 54% of the American population will be minorities. With this changing cultural landscape has come some contentious political divides.

In this study, the authors utilized a novel psychophysiological probe of pain-opioid conditioned associations, the cue-primed reactivity (CPR) task, to assess associative learning and second-order conditioning effects among chronic pain patients taking long-term opioid analgesics.

This exploratory study examined the three domains of self-extension proposed by William James' Constituents of Self—the psychological, social, and material domains. A novel analytic method, Multidimensional Scaling (MDS-T), was used to represent the structure of James' self-extension domains in geometric space for a large sample of American adults (N = 1181).