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Impaired frontostriatal functional connectivity among chronic opioid using pain patients is associated with dysregulated affect

Preclinical studies have shown effects of chronic exposure to addictive drugs on glutamatergic‐mediated neuroplasticity in frontostriatal circuitry. These initial findings have been paralleled by human functional magnetic resonance imaging (fMRI) research demonstrating weaker frontostriatal resting‐state functional connectivity (rsFC) among individuals with psychostimulant use disorders. We hypothesized that prescription opioid users with chronic pain, as compared with healthy control subjects, would evidence weaker frontostriatal rsFC coupled with less frontostriatal gray matter volume (GMV).

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Brief Mindfulness-Based Interventions for Acute and Chronic Pain: A Systematic Review

Nonpharmacologic approaches have been characterized as the preferred means to treat chronic noncancer pain by the Centers for Disease Control and Prevention. There is evidence that mindfulness-based interventions (MBIs) are effective for pain management, yet the typical MBI may not be feasible across many clinical settings due to resource and time constraints. Brief MBIs (BMBIs) could prove to be more feasible and pragmatic for safe treatment of pain. This article systematically reviews evidence of BMBI's effects on acute and chronic pain outcomes in humans.

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Brief mindfulness-based interventions for acute and chronic pain: A systematic review

Nonpharmacologic approaches have been characterized as the preferred means to treat chronic noncancer pain by the Centers for Disease Control and Prevention. There is evidence that mindfulness-based interventions (MBIs) are effective for pain management, yet the typical MBI may not be feasible across many clinical settings due to resource and time constraints. Brief MBIs (BMBIs) could prove to be more feasible and pragmatic for safe treatment of pain.

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Standing on the Shoulders of Giants: Matthew O. Howard as a Mentor and His Influence on the Science of Mindfulness as a Treatment for Addiction

It is difficult to estimate the impact of a scholar. Conventional metrics such as citation counts, h-indexes, publications in top-tier journals, and federal grants all provide some objective indication of scholarly impact, but these indices fail to capture the holistic and historical context of a scholar’s influence on the development and emergence of entire fields of inquiry. As his student and colleague, I believe that Matthew Owen Howard, PhD, exerted a singular influence on social work research, and his scholarly efforts helped give rise to a new and critically important field of scientific investigation: the study of mindfulness as a treatment for addiction.

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Last Updated: 12/12/23