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Psychological & Metabolic Health and Atypical Antipsychotic Use among Dual Status Youth

Principal Investigator (PI) / Project Lead:

JAGGERS, JEREMIAH

Funding Organization:

University of Utah Research Foundation & College of Social Work

RFP / FOA:

Research Incentive Seed Grant Program – College of Social Work

Award Number:

None

Project Period:

4/1/2023 – 3/31/2024, NCE 4/30/2025

Total Funding:

$13,800

Project Status:

In progress

 

Project Description:

The primary aim of this study is to evaluate the longitudinal effect of anti-psychotic medication use on metabolic conditions, and exacerbation and manifestation of psychiatric symptoms.

 

Abstract:

Research on atypical antipsychotics has demonstrated long-term negative health consequences. However, this research has not been extended to maltreated and delinquent youth. The primary aim of this study is to evaluate the longitudinal effect of anti-psychotic medication use on metabolic conditions, and exacerbation and manifestation of psychiatric symptoms. The study will use a tailored dataset from the Utah Population Database, which will include physical and mental healthcare data, justice system contact, child welfare involvement, and prescriptive data. Cross-lagged longitudinal analysis will be used to ascertain the long-term impact of atypical antipsychotics in a cohort of individuals who are 10 – 14 years old in 2013, with all available health data through 2020. Sub-group analysis will compare dual status youth, child welfare involved youth, juvenile justice system involved youth, and youth with no system contact. The long term goal of this research is to a) determine the impact of atypical antipsychotic medications on at-risk youth and b) inform development of best prescribing practices to limit the potentially deleterious effect on physical and mental health.

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Last Updated: 11/2/23